Kaeberlein Research Identifies New Aging Pathway

Scientists from UW Medicine Department of Pathology have identified a previously unknown link between aging and the cellular response to oxygen, known as the hypoxic response.  Under normal oxygen conditions the hypoxic response is kept "off".  The new study, published in the journal Science, found that turning on the hypoxic response in the nematode C. elegans slows aging and increases resistance to the toxic proteins that cause Alzheimer's and Huntington's diseases in people.