Pathology Academic Programs Courses

Graduate Program

UW Time Schedule

Required

PATH 501 - Pathology Proseminar
Course Director: Varies
Prerequisite: Permission of instructor
Quarters Offered: AWSp (must complete 3 quarters)
Credits: 1, Graded
Small group discussions and presentations by students based on critical reading of original papers, or on concurrent seminars, in many areas of experimental pathology and medicine.

Topic varies by quarter.  The Path 501 offered every Autumn quarter is an introduction to reading and critiquing the scientific literature.

3 quarters are required.
PATH 507 - Introduction to Pathology Research
Course Director: Campbell, Smith
Prerequisite: Permission of instructor
Quarters Offered: A
Credits: 2, CR/NCR
Current developments and approaches to investigation of the molecular and cellular basis of disease. Members of the Pathology faculty present and discuss their own research projects. Credit/no credit only.
PATH 512 - Molecular Basis of Disease: Pathology Methods for Graduate Students
Course Director: Bowen-Pope
Prerequisite: Permission of instructor
Quarters Offered: A
Credits: 1.5
Introduction to basic cell/tissue architecture and processes that underlie homeostasis and diseases, including apoptosis, necrosis, stem cells, inflammation, granulation tissue, fibrosis, tissue regeneration/repair.  Emphasis on the experimental techniques used to study tissue and cell architecture, including imaging technologies.
PATH 513 - Molecular Basis of Disease: Mechanisms of Neurodegeneration
Course Director: Keene
Prerequisite: Permission of instructor
Quarters Offered: A
Credits: 1.5, Graded
Introduction to the cellular and molecular mechanisms that underlie neurodegenerative diseases, including introduction ot the normal development and anatomy of the central nervous system, a review of epidemioloogic, genetic, and clinical research tools used in the investigation of these diseases, and a systematic review of the major neurodegenerative diseases.
PATH 515 - Molecular Basis of Disease: Atherosclerosis and Myocardial Infarction
Course Director: Murry
Prerequisite: Permission of instructor
Quarters Offered: Spring of even-numbered years
Credits: 1.5, Graded
Introduces medically important diseases and experimental approaches to understanding the basis of diseases and their treatments. Covers artherosclerosis, including lipids, extracellular matrix, cell signaling, inflammation, and downstream complications such as myocardial infarction and arrhythmias.

 
PATH 516 - Molecular Basis of Disease: Human Genetic Disease
Course Director: Byers
Prerequisite: Permission of the instructor
Quarters Offered: Sp
Credits: 3, Graded
Introduces the underlying mechanisms in human genetic disorders, ranging from the single nucleotide through genomic instability, and chromosomal rearragements. Includes tissue- and organ-specific examples of the manner in which these disorders provide insights into human biology.
PATH 517 - Biology and Pathology of Aging
Course Director: Kaeberlein
Prerequisite: Coursework in biology, biochemistry, molecular biology, and genetics
Quarters Offered: W even years (2012)
Credits: 3, Graded
Surveys the biology and pathologies of the aging phenomena in multiple species and at multiple organismal levels from whole animals to molecules.
PATH 520 - Experimental Pathology Seminar
Course Director: Bowen-Pope
Prerequisite: None
Quarters Offered: AWSp
Credits: 1 Credit/No Credit
This is "Pathology Presents", the Pathology departmental seminar series.  All Pathology faculty, post-docs, and graduate students are encouraged to attend these seminars.  Pathology graduate students are required to register for PATH 520 every quarter until the quarter of the Final Defense.   To obtain credit for a quarter, you are required attend at least 50% of the seminars offered during that quarter.  If there is a sufficient reason why this is not possible for a given quarter, eg course schedule conflict, you can petition to the Program Director, Dan Bowen Pope, for a waiver.  Attendance is monitored by online student-speaker evaluations.  There is no exam for this course. 
PATH 544 General and Systemic Pathology
Course Director: Narayanan
Prerequisite: None
Quarters Offered: WSp
Credits: 5 total (Winter plus Spring)
This is a 2-quarter course: 3 credits for Winter and 2 credits for Spring.  Both quarters need to be taken to complete the course.  At the end of Winter quarter, an “X” shows up in your grade sheet.  It gets converted to a grade when you complete the course at the end of Spring quarter.  The Winter quarter covers general principles of disease mechanisms.  The Spring quarter covers pathologies of specific organ systems.
PATH 551 Lab Rotations
Course Director: Varies
Prerequisite: Permission of instructor
Quarters Offered: AWSpSu
Credits: Up to 10, CR/NCR
Student is given a work area and a research project in the laboratory of a Pathology Graduate Faculty member.  At the end of the quarter, the student gives a formal 10 minute PowerPoint presentation of the project followed by a question/answer session then a group critique of presentation style.
PATH 600 - Independent Study or Research
Course Director: Varies
Prerequisite: Permission of instructor
Quarters Offered: AWSpSu
Credits: Up to 10, CR/NCR
Register for PATH 600 for research prior to establishing your Thesis Supervisory Committee.  Register for enough credits to bring your total to 10 for A,W, and Sp quarters, and for 2 credits for Summer quarter.
PATH 800 - Doctoral Dissertation
Course Director: Varies
Prerequisite: Permission of instructor
Quarters Offered: AWSpSu
Credits: Up to 10, CR/NCR
Register for PATH 800 for research after establishing your Thesis Supervisory Committee.  Register for enough credits to bring your total to 10 for A,W, and Sp quarters, and for 2 credits for Summer quarter.
BIOST 511 - Medical Biometry
Course Director: N/A
Prerequisite:
Quarters Offered: ASu
Credits: 4, Graded
Presentation of the principles and methods of data description and elementary parametric and nonparametric statistical analysis. Examples are drawn from the biomedical literature, and real data sets are analyzed by the students after a brief introduction to the use of standard statistical computer packages. Statistical techniques covered include description of samples, comparison of two sample means and proportions, simple linear regression and correlation.
CONJ 538 - Genetic Instability and Cancer
Course Director: Maizels, Monnat
Prerequisite: Permission of instructor
Quarters Offered:
Credits: 1-1.5, Graded
Seminar focusing on molecular pathways that maintain genomic stability in all cells and that carry out programmed changes in genomic structure in the immune system. Special attention devoted to understanding how failure in these pathways leads to genomic instability and malignancy.
CONJ 539 - Biological Basis of Neoplasia
Course Director: Kemp, Zarbl
Prerequisite: Introductory biochemistry and cell biology
Quarters Offered: Sp
Credits: 1.5, Graded
Lecture/discussion on cellular and molecular mechanisms underlying phenotypes associated with cancer, including genetic pre-disposition, injury, and instability; alteration in control of cell division and cell death; failure of differentiation; tumor angiogenesis and metatasis. Molecular biology of tractable model systems is emphasized.

Recommended

CONJ 531 - Signaling Mechanisms in Excitable Cells
Course Director: Hille
Prerequisite: Comprehensive undergraduate course in general biochemistry and molecular biology or permission of instructor
Quarters Offered: A
Credits: 1.5, Graded
Membrane electricity. Structure and roles of voltage-gated and ligand-gated ion channels in electrical signaling. Calcium as a second messenger. Exocytosis and its regulation. Phototransduction in photoreceptors.
CONJ 532 - Signal Transduction from the Cell Membrane to the Nucleus
Course Director: Beavo, Moon, Storm
Prerequisite: Basic knowledge of biochemistry
Quarters Offered: A
Credits: 1.5, Graded
Intracellular signaling pathways leading from cell membrane receptors to nucleus. Pathways activated by seven transmembrane receptors and G-proteins, insulin/PI3 kinase, nitric oxide and WNTs and mechanisms of signal termination. Cytokine/Jak/Stat signaling and role of subcellular localization in signal transduction.

Other Graduate Courses

PATH 511 - Topics in Experimental Pathology
Course Director: Campbell, Mahoney
Prerequisite: Permission of instructor
Quarters Offered: AWSpSu
Credits: 1-2, max 10
Special in topics in experimental pathology. 

Offered infrequently.
PATH 514/CONJ514 - Molecular Medicine
Course Director: Rosen
Prerequisite: N/A
Quarters Offered: W
Credits: 3
Graduate-level introduction to the interplay of basic science and clinical medicine. Covers inflammation, vascular disease, metabolic disorders, cancer biology, and molecular-, gene-, and cell-based therapies. Each topic introduced with a patient history.
PATH 530 - Human Cytogenetics
Course Director: Disteche
Prerequisite: Permission of instructor
Quarters Offered: Sp, even Years
Credits: *, max 4
Sources and methods of preparation and identification of human chromosomes. Molecular structure and mapping of chromosomes. Human cytogenetic pathology: karyotype-phenotype interactions, chromosome breakage, and cancer cytogenetics.

 
PATH 555 - Environmental Pathology
Course Director: Montine
Prerequisite: PATH410 or PATH444 or HUBIO520; recommended ENVH514 and ENVH515.
Quarters Offered: Even years as requested
Credits: 3
Modern morphologic, cell biological and molecular approaches to environmental disease associated with exposure/predisposition. Lectures, seminar discussion, and student presentations.