Pathology Academic Programs Courses

Graduate Program

UW Time Schedule

Required

PATH 501 - Pathology Proseminar Course Director: Varies Prerequisite: Permission of instructor Quarters Offered: AWSp (must complete 3 quarters) Credits: 1, Graded	Small group discussions and presentations by students based on critical reading of original papers, or on concurrent seminars, in many areas of experimental pathology and medicine. Topic varies by quarter. The Path 501 offered every Autumn quarter is an introduction to reading and critiquing the scientific literature. 3 quarters are required.
PATH 507 - Introduction to Pathology Research Course Director: Campbell, Smith Prerequisite: Permission of instructor Quarters Offered: A Credits: 2, CR/NCR	Current developments and approaches to investigation of the molecular and cellular basis of disease. Members of the Pathology faculty present and discuss their own research projects. Credit/no credit only.
PATH 512 - Molecular Basis of Disease: Pathology Methods for Graduate Students Course Director: Bowen-Pope Prerequisite: Permission of instructor Quarters Offered: A Credits: 1.5	Introduction to basic cell/tissue architecture and processes that underlie homeostasis and diseases, including apoptosis, necrosis, stem cells, inflammation, granulation tissue, fibrosis, tissue regeneration/repair. Emphasis on the experimental techniques used to study tissue and cell architecture, including imaging technologies.
PATH 513 - Molecular Basis of Disease: Mechanisms of Neurodegeneration Course Director: Keene Prerequisite: Permission of instructor Quarters Offered: A Credits: 1.5, Graded	Introduction to the cellular and molecular mechanisms that underlie neurodegenerative diseases, including introduction ot the normal development and anatomy of the central nervous system, a review of epidemioloogic, genetic, and clinical research tools used in the investigation of these diseases, and a systematic review of the major neurodegenerative diseases.
PATH 515 - Molecular Basis of Disease: Atherosclerosis and Myocardial Infarction Course Director: Murry Prerequisite: Permission of instructor Quarters Offered: Spring of even-numbered years Credits: 1.5, Graded	Introduces medically important diseases and experimental approaches to understanding the basis of diseases and their treatments. Covers artherosclerosis, including lipids, extracellular matrix, cell signaling, inflammation, and downstream complications such as myocardial infarction and arrhythmias.
PATH 516 - Molecular Basis of Disease: Human Genetic Disease Course Director: Byers Prerequisite: Permission of the instructor Quarters Offered: Sp Credits: 3, Graded	Introduces the underlying mechanisms in human genetic disorders, ranging from the single nucleotide through genomic instability, and chromosomal rearragements. Includes tissue- and organ-specific examples of the manner in which these disorders provide insights into human biology.
PATH 517 - Biology and Pathology of Aging Course Director: Kaeberlein Prerequisite: Coursework in biology, biochemistry, molecular biology, and genetics Quarters Offered: W even years (2012) Credits: 3, Graded	Surveys the biology and pathologies of the aging phenomena in multiple species and at multiple organismal levels from whole animals to molecules.
PATH 520 - Experimental Pathology Seminar Course Director: Bowen-Pope Prerequisite: None Quarters Offered: AWSp Credits: 1 Credit/No Credit	This is "Pathology Presents", the Pathology departmental seminar series. All Pathology faculty, post-docs, and graduate students are encouraged to attend these seminars. Pathology graduate students are required to register for PATH 520 every quarter until the quarter of the Final Defense. To obtain credit for a quarter, you are required attend at least 50% of the seminars offered during that quarter. If there is a sufficient reason why this is not possible for a given quarter, eg course schedule conflict, you can petition to the Program Director, Dan Bowen Pope, for a waiver. Attendance is monitored by online student-speaker evaluations. There is no exam for this course.
PATH 544 General and Systemic Pathology Course Director: Narayanan Prerequisite: None Quarters Offered: WSp Credits: 5 total (Winter plus Spring)	This is a 2-quarter course: 3 credits for Winter and 2 credits for Spring. Both quarters need to be taken to complete the course. At the end of Winter quarter, an “X” shows up in your grade sheet. It gets converted to a grade when you complete the course at the end of Spring quarter. The Winter quarter covers general principles of disease mechanisms. The Spring quarter covers pathologies of specific organ systems.
PATH 551 Lab Rotations Course Director: Varies Prerequisite: Permission of instructor Quarters Offered: AWSpSu Credits: Up to 10, CR/NCR	Student is given a work area and a research project in the laboratory of a Pathology Graduate Faculty member. At the end of the quarter, the student gives a formal 10 minute PowerPoint presentation of the project followed by a question/answer session then a group critique of presentation style.
PATH 600 - Independent Study or Research Course Director: Varies Prerequisite: Permission of instructor Quarters Offered: AWSpSu Credits: Up to 10, CR/NCR	Register for PATH 600 for research prior to establishing your Thesis Supervisory Committee. Register for enough credits to bring your total to 10 for A,W, and Sp quarters, and for 2 credits for Summer quarter.
PATH 800 - Doctoral Dissertation Course Director: Varies Prerequisite: Permission of instructor Quarters Offered: AWSpSu Credits: Up to 10, CR/NCR	Register for PATH 800 for research after establishing your Thesis Supervisory Committee. Register for enough credits to bring your total to 10 for A,W, and Sp quarters, and for 2 credits for Summer quarter.
BIOST 511 - Medical Biometry Course Director: N/A Prerequisite: Quarters Offered: ASu Credits: 4, Graded	Presentation of the principles and methods of data description and elementary parametric and nonparametric statistical analysis. Examples are drawn from the biomedical literature, and real data sets are analyzed by the students after a brief introduction to the use of standard statistical computer packages. Statistical techniques covered include description of samples, comparison of two sample means and proportions, simple linear regression and correlation.
CONJ 538 - Genetic Instability and Cancer Course Director: Maizels, Monnat Prerequisite: Permission of instructor Quarters Offered: Credits: 1-1.5, Graded	Seminar focusing on molecular pathways that maintain genomic stability in all cells and that carry out programmed changes in genomic structure in the immune system. Special attention devoted to understanding how failure in these pathways leads to genomic instability and malignancy.
CONJ 539 - Biological Basis of Neoplasia Course Director: Kemp, Zarbl Prerequisite: Introductory biochemistry and cell biology Quarters Offered: Sp Credits: 1.5, Graded	Lecture/discussion on cellular and molecular mechanisms underlying phenotypes associated with cancer, including genetic pre-disposition, injury, and instability; alteration in control of cell division and cell death; failure of differentiation; tumor angiogenesis and metatasis. Molecular biology of tractable model systems is emphasized.

Recommended

CONJ 531 - Signaling Mechanisms in Excitable Cells Course Director: Hille Prerequisite: Comprehensive undergraduate course in general biochemistry and molecular biology or permission of instructor Quarters Offered: A Credits: 1.5, Graded	Membrane electricity. Structure and roles of voltage-gated and ligand-gated ion channels in electrical signaling. Calcium as a second messenger. Exocytosis and its regulation. Phototransduction in photoreceptors.
CONJ 532 - Signal Transduction from the Cell Membrane to the Nucleus Course Director: Beavo, Moon, Storm Prerequisite: Basic knowledge of biochemistry Quarters Offered: A Credits: 1.5, Graded	Intracellular signaling pathways leading from cell membrane receptors to nucleus. Pathways activated by seven transmembrane receptors and G-proteins, insulin/PI3 kinase, nitric oxide and WNTs and mechanisms of signal termination. Cytokine/Jak/Stat signaling and role of subcellular localization in signal transduction.

Other Graduate Courses

PATH 511 - Topics in Experimental Pathology Course Director: Campbell, Mahoney Prerequisite: Permission of instructor Quarters Offered: AWSpSu Credits: 1-2, max 10	Special in topics in experimental pathology. Offered infrequently.
PATH 514/CONJ514 - Molecular Medicine Course Director: Rosen Prerequisite: N/A Quarters Offered: W Credits: 3	Graduate-level introduction to the interplay of basic science and clinical medicine. Covers inflammation, vascular disease, metabolic disorders, cancer biology, and molecular-, gene-, and cell-based therapies. Each topic introduced with a patient history.
PATH 530 - Human Cytogenetics Course Director: Disteche Prerequisite: Permission of instructor Quarters Offered: Sp, even Years Credits: *, max 4	Sources and methods of preparation and identification of human chromosomes. Molecular structure and mapping of chromosomes. Human cytogenetic pathology: karyotype-phenotype interactions, chromosome breakage, and cancer cytogenetics.
PATH 555 - Environmental Pathology Course Director: Montine Prerequisite: PATH410 or PATH444 or HUBIO520; recommended ENVH514 and ENVH515. Quarters Offered: Even years as requested Credits: 3	Modern morphologic, cell biological and molecular approaches to environmental disease associated with exposure/predisposition. Lectures, seminar discussion, and student presentations.