Brian Hayes

Campbell Lab

E-MAIL:
hayesb2 at uw.edu
MAIL/BOX #:
357705
OFFICE LOCATION:
HSC- Rm- K-085
PHONE NUMBER:
206-616-4796

 

Reseach Background and Interests

My current research is focused on determining the contribution of platelet derived growth factor receptor alpha (PDGFRα) and its ligands to fibrotic liver disease. Liver fibrosis is a common feature in chronic liver disease of diverse etiologies. Treatment of liver disease could prevent the incidence of cirrhosis and liver cancer. The majority of cells in the liver do not express PDGFRα. Hepatic stellate cells, the cell type responsible for liver fibrosis, on the other hand, express PDGFRα and respond to PDGFRα stimulation. I am interested in how manipulation of PDGFRα activation can affect stellate cell proliferation and migration both in vitro and in vivo. The results could support targeted disruption of PDGFRα as a therapeutic strategy.

Year entered program

2008

Education

University of Illinois, Biology, 2002

Lab Information

Current Lab:

Jean Campbell, PhD

Rotation Labs:

Dan Bowen-Pope, PhD, Professor

Jean Campbell, PhD, Assistant Professor

Raymond Monnat, MD, Professor

Publications

PubMed