M3D PhD Program

The M3D PhD Program trains students to use advances in basic sciences to solve problems relevant to human disease; and to use insights from human disease processes to solve fundamental biological problems. Three core courses focus on mechanisms of disease, the impact of basic science on medicine, and human genetics, providing a rigorous intellectual foundation. Each student participates in Chief of Medicine rounds, and some students may also opt for a mentored clinical rotation in a more focused area relevant to the student’s thesis research. Students choose electives reflecting their own interests from the deep and varied menu offered by UW basic science and engineering departments.  The M3D PhD Program is a collaborative effort among the Departments of Medicine, Pathology and Pediatrics.  Thesis research is supervised by two mentors, one a basic scientist (the Research Mentor) and the other a clinician scientist (the Clinical Mentor), enabling students to complement their experimental work with exposure to relevant problems in the clinic.  Students may  identify Research Mentors from qualified faculty members with a primary appointment in one of those participating departments; faculty from other departments may train M3D PhD students, provided that the faculty member commits to support the student while in training.  The M3D Program is designed for students to complete PhD training in five years, ready to take the next step in careers in academia, biotech, the pharmaceutical industry, education, publishing and public policy.

Dual Mentorship: Research and Clinical Mentors

A key feature of M3D PhD Program training is dual mentorship of each student.  The Research Mentor provides laboratory space and supervises thesis research; and the Clinical Mentor promotes and facilitates awareness of the clinical significance of the project.

Research Mentors

The Research Mentor is the direct supervisor of student research, providing guidance on choice of project, advice on experimental strategies, and support in developing communication skills necessary to career development.

Clinical Mentors

The Clinical Mentor promotes and facilitates awareness of the clinical significance of the project. Faculty with clinical expertise in any department may serve as Clinical Mentors.

M3D Student Handbook

The M3D Program guidelines and curriculum along with Graduate School policies and procedures can be found in the M3D Student Handbook

We encourage diversity among our students!

As befits an interdisciplinary program like M3D, our students represent diverse intellectual interests and scientific and personal backgrounds, and they seek to achieve a spectrum of professional and personal goals.   We strive to create a warm and welcoming community for everyone.  As part of this commitment, we embrace the provisions of the Americans with Disabilities Act and we actively seek applicants who require accommodation, as further detailed on the UW Disability Services Office  website.

 

M3D PhD Program

M3D Directors and Co-Directors

Faculty

Nancy Maizels, PhD, Director, Professor of Immunology and Biochemistry; Adjunct Professor of Pathology
Conrad Liles, MD PhD, Co-Director, Associate Chair and Professor of Medicine; Adjunct Professor of Global Health, Pathology and Pharmacology
William Mahoney PhD, Co-Director, Associate Professor of Pathology
Mark Majesky, PhD, Co-Director, Professor of Pediatrics and Pathology, Seattle Childrens Research Center for Developmental Biology and Regenerative Medicine
Daniel Promislow, PhD, Co-Director, Professor of Pathology and Biology

M3D PhD Program

M3D PhD Program Curriculum

The M3D PhD Program is designed for students to complete PhD training in five years.  Students complete core coursework in the first year of graduate school while carrying out rotations in two or three different laboratories, as outlined below.  Students choose thesis laboratories by the end of the first year.  In Year 2, students TA for one quarter and take the General Examination.  In Years 3-5, students devote themselves to thesis research.

M3D emphasizes the significance of thesis research for improved understanding and treatment of human disease.  Students focus on this significance in a Capstone Presentation, in Year 4.  The thesis defense, in Year 5, students discuss their research and its scientific and medical impact.

M3D Coursework, Year 1

Fall Quarter Winter Quarter Spring Quarter

Core 1: 

MolMed514: Molecular Medicine (Liles)

Core 2:

Path 550: Mechanisms of Disease (Liles)

 

Path 516: Human Genetics (Byers)

Path 551: Lab Rotation 1 MolMed540: Chief of Medicine Rounds (Liles) MolMed540: Chief of Medicine Rounds (Liles)
Path 520: Experimental Pathology Seminar Path 551: Lab Rotation 2 Path 551: Lab Rotation 3
Responsible Conduct of Research

 

Path 520: Experimental Pathology Seminar Path 520: Experimental Pathology Seminar



Additional electives (suggested by previous M3D students)
Path 580:  Mitochondria & Metabolism in the Pathogenesis of Human Disease (Hawkins/Marcinek/Tian) Path 517:  The Biology and Pathology of Aging (Kennedy/Herr) Path 558: Integrative Omics (Davis/Young) TBA
Path 513:  Mechanisms of Neurodegeneration (Keene) Path511:  Pathogenesis of Cancer (Risques/Chen) Path 515: Cardiovascular Pathology (Mahoney)
PABIO 551: Biochenistry and Genetics of Pathogens and their Hosts MCB 522: Developmental Basis of Human Disease Path 530: Human Cytogentogenetics (Lu/Disteche)
NUTR 520: Nutrition and Metabolism NUTR 521: Nutrition and Metabolism MolMed 504: Challenges in [topic area changes annually
GENOME 553: Genetic Analysis Conj 529: Cell Migration Conj 530: Directing Stem Cells Toward Regenerative Medicine
GENOME 552: Genomics NUTR 522: Nutrition and Metabolism
CSE 527: Computational Analysis
Conj 531: Signaling Mechanisms in Excitable Cells
Conj 532: Signal Transduction from the Cell Membrane to the Nucleus
Conj 537: Mechnaisms of Transcriptional Regulation

 

 

Statistics: M3D students are required to demonstrate or achieve mastery of basic statistics/large dataset handling, via research training or an online or UW course.

Electives

Students may choose electives from the many courses offered by UW Departments of Biochemistry, Bioengineering, Genome Sciences, Immunology, Microbiology, Pathology, Pharmacology, Physiology & Biophysics; or from courses offered by the interdisciplinary Molecular & Cellular Biology or Neurosciences Programs.

M3D PhD Program

Molecular Medicine & Mechanism of Disease (M3D)

The M3D Ph.D. Program trains students to use advances in basic sciences to solve problems relevant to human disease; and to use insights from human disease to processes to solve fundamental biological problems. Three core courses focus on mechanism of disease, the impact of basic science on medicine, and human genetics, providing a rigorous intellectual foundation. Each student participates in Chief of Medicine rounds, and in a mentored clinical rotation, in the broad area of human genetics or in a more focused area relevant to the student’s thesis research. Students also choose electives reflecting their own interests from the deep and varied menu offered by UW basic science and engineering departments. Thesis research is supervised by two mentors, one a basic scientist and the other a clinician scientist. Students complement their experimental work with exposure to relevant problems in the clinic. The M3D Program is designed for students to complete Ph.D. training in five years, ready to take the next step in careers in academia, biotech, the pharmaceutical industry, education, publishing and public policy.

Applying to the M3D PhD Program

1. Create an application online through the University of Washington Graduate School website.

  • Select “Pathology” from the menu of departments and programs. The interdisciplinary M3D program is based in the Department of Pathology
  • Complete all sections of the application
  • Upload unofficial transcripts
  • Self report GRE scores
  • Letters of reference: the application will ask you to identify those who will be submitting letters on your behalf and provide their email addresses. The application system will contact them automatically with instructions about how to submit their letters. Be sure you contact them first to confirm that they are willing and able to provide a recommendation.

2. Pay the application fee online using a Mastercard or Visa debit/credit card. For current information about the fee and fee waivers, please see the Graduate School Application Information page. Please note that the fee is assessed by the Graduate School, not the M3D program. The M3D program therefore cannot approve fee waivers–all requests must be made directly to the Graduate School.

3. Have your official GRE score report submitted directly by ETS. The UW Institution Code is 4854.

4. For international or ESL applicants only, a Certified TOEFL Score Report must be submitted directly by ETS. The UW Institution Code is 4854.

5. All materials must be received by December 3, 2018

6. Top candidates will be invited to visit the M3D PhD Program and interview with our faculty.

7. The first round of admissions decisions will be made in late February or early March 2019

The Molecular Medicine and Mechanism of Disease (M3D) Ph.D. Program is committed to recruiting diverse participants, including students with a broad spectrum of scientific interests, students from underrepresented racial and ethnic groups, students with physical or mental impairments that limit any major life activity, and students from economically or educationally disadvantaged backgrounds. Addition information about resources for student applicants with disabilities is available on the (DRS) website: http://depts.washington.edu/uwdrs/

For more information, please contact Megan Barker at m3d@uw.edu
www.depts.washington.edu/molmed/m3dphd/

Diversity Resources for UW Graduate Applicants
Office of Minority Affairs and Diversity
Graduate Opportunities and Minority Achievement Program (GO-MAP)
Center for Equity, Diversity & Inclusion (CEDI)
Graduate School Diversity

Resources for Student Applicants with Physical or Mental Impairments
Disabilities Services Office (DSO) offers resources and services for UW staff, faculty and campus visitors with physical and mental impairments.
Disabilities, Opportunities, Internetworking and Technology (DO-IT) (Disabilities, Opportunities, Internetworking, and Technology) promotes the use of computer and networking technologies to increase independence, productivity, and participation in education and employment.
The Access Technology Center (ATC) serves users with disabilities, allowing full use of campus computing resources. ATC staff provides accessibility consultations and instructs users in accessible hardware and software basics.
Title IX/ADA Coordinator Office Program provides University-wide compliance support to facilitate equal opportunity and ensure compliance with relevant University policies and local, state, and federal laws.
UW Disability Resources for Students (DRS) is dedicated to ensuring access and inclusion for all students with disabilities on the Seattle campus enrolled in our undergraduate, graduate, professional, Evening Degree and Access programs for over 38 years

Printable Recruitment Flyers

2019 M3D recruitment flier final

2019 Molecular Medicine & Mechanisms of Disease Flyer (Large Print)

 

M3D PhD Program

University 501 (U501) is a self-guided, online resource designed for graduate students and is intended to help prepare you for your arrival to and start at the University of Washington. Go HERE for more information.

Documents

M3D IDP First Year Students

M3D IDP Y2 and beyond

M3D Rotation Evaluation Form

M3D Presentation Evaluation Form

M3D Progress Report FINAL updated 062018

M3D General Exam Guidelines

 

Graduate School forms

Petition for Reduced Enrollment This form is to be filled out your final quarter and will ensure continued GAIP coverage.

 

Health and Wellness

Hall Health Center

Hall Health Mental Health

UW Counseling Center

Graduate Appointee Insurance Program (GAIP)

Green Dot  The aim of Green Dot is to prevent and reduce sexual assault & relationship violence at UW by engaging students as leaders and active bystanders who step in, speak up, and interrupt potential acts of violence.

 

Graduate School links

Graduate School- MyGrad Program

Dates and Deadlines

Thesis/Dissertation Information

UAW 4121 – Union for Academic Student Employees at UW