The CDL offers a testing panel sequencing 5 genes involved in familial aneurysmal disorders: ACTA2, COL3A1, SMAD3, TGFBR1 and TGFBR2. This panel is recommended for those individuals with vascular complications (arterial aneurysms, dissection, rupture) and a family history of similar complications that do not fit into a clear syndrome. Please consult our Test Guide on Ehlers-Danlos syndrome and Familial Aneurysm for more information on the correct test to order.
Specimen Requirements: 5 cc of blood drawn in EDTA (lavender top tube) or DNA
| Vascular Disease Panel | |
| CPT CODE | DESCRIPTION |
|---|---|
| 83898 | PCR amplification ACTA2 (x9) |
| 83904 | Mutation identification by sequencing ACTA2 (x9) |
| 83912 | Interpretation and Report ACTA2 |
| 83898 | PCR amplifications COL3A1 (x25) |
| 83904 | Mutation identification by sequencing COL3A1 (x32) |
| 83912 | Interpretation and Report COL3A1 |
| 83898 | PCR amplification SMAD3 (x8) |
| 83904 | Mutation identification by sequencing SMAD3 (x8) |
| 83912 | Interpretation and Report SMAD3 |
| 83898 | PCR amplification TGFBR1/2 (x16) |
| 83904 | Mutation identification by sequencing TGFBR1/2 (x18) |
| 83912 | Interpretation and Report TGFBR1/2 |
| TOTAL | $1890.00 |
| DNA Extraction from Blood Sample | |
| CPT CODE | DESCRIPTION |
|---|---|
| 83891 | Extraction of highly purified DNA |
| TOTAL | $50.00 |