Path Grand Rounds: Biomarkers in Barrett Esophagus

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Speaker

Melissa Upton, MD & Won-Tak Choi, MD, PhD
Department of Pathology
University of Washington


Date & Time

April 1, 2015 at 12:00pm - 1:00pm

Location

UWMC, NE110 conference room

Calendar

Path Grand Rounds

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Add to Calendar 04/01/2015 12:00 PM 04/01/2015 01:00 PM America/Los_Angeles Path Grand Rounds: Biomarkers in Barrett Esophagus Path Grand Rounds: Biomarkers in Barrett Esophagus

Melissa Upton, MD & Won-Tak Choi, MD, PhD
Department of Pathology
University of Washington
Why Attend? Adenocarcinoma of the esophagus has increased in incidence by 700% over the past 30 years, and it is usually associated with Barrett esophagus and long-standing gastroesophageal reflux disease. Although the association with Barrett esophagus is well known, most patients present with adenocarcinoma, without prior screening or surveillance. In addition, endoscopic surveillance protocols for patients with Barrett esophagus are time-consuming, invasive and costly. What are the best biomarkers to identify patients at risk for carcinoma to permit early detection or treatment of pre-malignant conditions? Dr. Won-Tak Choi will present results of a recent project on DNA flow cytometry, and Dr. Upton will present an overview of the scope of the issue and the pros and cons of current testing. Melissa Upton, MD Professor, Department of Pathology University of Washington Won-Tak Choi, MD, PhD AP/CP Resident, Department of Pathology University of Washington Please Note: This lecture can also be viewed via teleconference: HMC room 2NJ251 & VA room BD152
UWMC, NE110 conference room false MM/DD/YYYY

Description

Why Attend?

Adenocarcinoma of the esophagus has increased in incidence by 700% over the past 30 years, and it is usually associated with Barrett esophagus and long-standing gastroesophageal reflux disease. Although the association with Barrett esophagus is well known, most patients present with adenocarcinoma, without prior screening or surveillance. In addition, endoscopic surveillance protocols for patients with Barrett esophagus are time-consuming, invasive and costly. What are the best biomarkers to identify patients at risk for carcinoma to permit early detection or treatment of pre-malignant conditions? Dr. Won-Tak Choi will present results of a recent project on DNA flow cytometry, and Dr. Upton will present an overview of the scope of the issue and the pros and cons of current testing.

Melissa Upton, MD
Professor, Department of Pathology
University of Washington

Won-Tak Choi, MD, PhD
AP/CP Resident, Department of Pathology
University of Washington