Basic Biology of Aging: Aging & Cancer: Rival demons?

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Speaker

Judith Campisi, PhD
Buck Institute for Research on Aging


Date & Time

April 8, 2016 at 2:30pm - 3:30pm

Location

Health Sciences Building, K-069

Calendar

Basic Biology of Aging

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Add to Calendar 04/08/2016 02:30 PM 04/08/2016 03:30 PM America/Los_Angeles Basic Biology of Aging: Aging & Cancer: Rival demons? Basic Biology of Aging: Aging & Cancer: Rival demons?

Judith Campisi, PhD
Buck Institute for Research on Aging
Why Attend? Aging & Cancer: Rival demons? Aging is the largest risk factor for a host of chronic diseases. Why is this so? One widely accepted view holds that one or more basic aging process alters tissues and the systemic mi­lieu, making them vulnerable to loss of homeostasis and pa­thology. I will discuss the evidence that cellular senescence, a complex stress response that protects multicellular organisms from cancer, is a candidate basic aging process that can drive multiple age-related diseases. These diseases range from neu­rodegeneration to, ironically, late life cancer. I will also discuss new possibilities for maintaining the anti-cancer benefits of the senescence response while ameliorating its deleterious effects.
Health Sciences Building, K-069 false MM/DD/YYYY

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Why Attend?

Aging & Cancer: Rival demons?

Aging is the largest risk factor for a host of chronic diseases. Why is this so? One widely accepted view holds that one or more basic aging process alters tissues and the systemic mi­lieu, making them vulnerable to loss of homeostasis and pa­thology. I will discuss the evidence that cellular senescence, a complex stress response that protects multicellular organisms from cancer, is a candidate basic aging process that can drive multiple age-related diseases. These diseases range from neu­rodegeneration to, ironically, late life cancer. I will also discuss new possibilities for maintaining the anti-cancer benefits of the senescence response while ameliorating its deleterious effects.