Pathology Presents: Exploiting viruses to understand and treat cancer

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Speaker

Clodagh O'Shea, PhD
Associate Professor
Salk Insitute for Biological Studies

Faculty Sponsor

Pathology Graduate Students


Date & Time

May 25, 2016 at 4:30pm - 5:30pm

Location

Health Sciences Building, T-739

Calendar

Pathology Presents

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Add to Calendar 05/25/2016 04:30 PM 05/25/2016 05:30 PM America/Los_Angeles Pathology Presents: Exploiting viruses to understand and treat cancer Pathology Presents: Exploiting viruses to understand and treat cancer

Clodagh O'Shea, PhD
Associate Professor
Salk Insitute for Biological Studies
Why Attend? Exploiting viruses to understand and treat cancer The O'Shea lab is employing the help of a small DNA virus, called adenovirus, to both understand and treat cancer. Normally, cellular replication is tightly controlled. However, both DNA viruses and tumor cells sabotage such controls to drive their respective pathological propagation, albeit with one small difference: In tumor cells the key cellular players are targeted via mutations, while in infected cells viral proteins achieve the same end. Not surprisingly, many of the cellular targets are the same.
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Why Attend?

Exploiting viruses to understand and treat cancer

The O'Shea lab is employing the help of a small DNA virus, called adenovirus, to both understand and treat cancer. Normally, cellular replication is tightly controlled. However, both DNA viruses and tumor cells sabotage such controls to drive their respective pathological propagation, albeit with one small difference: In tumor cells the key cellular players are targeted via mutations, while in infected cells viral proteins achieve the same end. Not surprisingly, many of the cellular targets are the same.