Russell Ross Endowed Lectureship: Monocyte Heterogeneity in Atherosclerosis

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Speaker

Catherine C. Hedrick, PhD
Professor
Division of Inflammation Biology
La Jolla Institute for Immunology

Faculty Sponsor

Michael Rosenfeld, PhD


Date & Time

October 30, 2019 at 4:30pm - 5:30pm

Location

HSB Room T-739

Calendar

Russell Ross Endowed Lectureship

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Add to Calendar 10/30/2019 04:30 PM 10/30/2019 05:30 PM America/Los_Angeles Russell Ross Endowed Lectureship: Monocyte Heterogeneity in Atherosclerosis Russell Ross Endowed Lectureship: Monocyte Heterogeneity in Atherosclerosis

Catherine C. Hedrick, PhD
Professor
Division of Inflammation Biology
La Jolla Institute for Immunology
Monocytes are innate immune cells that are quick responders to endothelial dysfunction that initiates atherosclerotic plaque development. Many studies have shown that monocytes are recruited by the damaged endothelium to the vessel wall, where the monocytes are exposed to oxidized lipids and cytokines and differentiate into macrophages. We now know that all monocytes are not the same. There is heterogeneity in blood monocytes that gives rise to different monocyte functions. We will discuss this heterogeneity and how it impacts cardiovascular disease. A special seminar dedicated to the memory and scientific legacy of Russell Ross, Professor and Chair, Department of Pathology, 1982-1994
HSB Room T-739 false MM/DD/YYYY

Description

Monocytes are innate immune cells that are quick responders to endothelial dysfunction that initiates atherosclerotic plaque development. Many studies have shown that monocytes are recruited by the damaged endothelium to the vessel wall, where the monocytes are exposed to oxidized lipids and cytokines and differentiate into macrophages. We now know that all monocytes are not the same. There is heterogeneity in blood monocytes that gives rise to different monocyte functions. We will discuss this heterogeneity and how it impacts cardiovascular disease.

A special seminar dedicated to the memory and scientific legacy of Russell Ross, Professor and Chair, Department of Pathology, 1982-1994