Yajuan J. Liu, PhD

Associate Professor

Yajuan J. Liu, PhD

E-mail:

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Office Location:

HSB - Room - H474-B

Mailing Address:

Box 357470
1959 NE Pacific St.
Seattle, WA 98195


Clinical and Research Background

Dr. Liu’s clinical specialties are clinical cytogenetics and clinical molecular genetics (ABMGG) for both constitutional genetic disorders in prenatal and postnatal settings and acquired genetic disorders including solid tumors and hematological neoplasms. Dr. Liu’s research interest is in translational medicine using genomic approaches to aid the understanding of the genetic and molecular etiologies of human diseases. Projects in Dr. Liu’s laboratory currently include: (1) Next generation sequencing solutions for cytogenetics to characterize numerical and structural chromosomal aberrations as well as copy neutral absence/loss of heterozygosity in human diseases. (2) Understanding the biological causes for the discordance between diagnostic genetic test results and non-invasive prenatal screening (NIPS) using cell-free DNA (3) Using RNA-seq to characterize gene fusions and juxtapositions in cancer, especially novel fusions in sarcoma (4) Identifying new molecular markers for hepatocellular carcinoma with various etiologies. The main goals are to develop molecular diagnostics using both conventional genetics methods and new genomic approaches to aid in precision diagnostics for personalized care. Dr. Liu is also involved in the training of medical residents and fellows and at the University of Washington.

Clinical Cytogenomics Laboratory

Cytogenetics and Genomics Laboratory

Board Certifications

Clinical Molecular Genetics, American Board of Medical Genetics and Genomics

Clinical Cytogenetics, American Board of Medical Genetics and Genomics

Academic and Medical Appointments

Associate Professor, Department of Pathology, University of Washington, Seattle, WA, 2016-Present

Assistant Professor, Department of Pathology, University of Washington, Seattle, WA, 2009-2016

Co-Director of Clinical Cytogenetics and Genomics Laboratory, University of Washington Medical Center, Seattle, WA, 2009-Present

Senior Research Scientist, Departments of Biology and Genome Sciences, University of Washington, Seattle, WA, 2002-2007

Education and Training

Clinical Molecular Genetics Fellow, Department of Medicine, University of Washington, Seattle, WA, 2012-2013

Postdoctoral Fellow, Cancer Genetics, Department of Medicine, University of Washington, Seattle, WA, 2007-2009

Clinical Cytogenetics Fellow, Department of Medicine, University of Washington, Seattle, WA, 2007-2009

Postdoctoral Fellow, Yeast Genetics and Molecular Evolution. Departments of Biology and Genome Sciences, University of Washington, Seattle, WA, 1995-2002

State University of New York, College of Environmental Science & Forestry, Syracuse, NY, Molecular Biology, Ph.D., 1995

Wuhan University, Hubei, China, Genetics, Master of Science, 1989

Wuhan University, Hubei, China, Cell Biology, Bachelor of Science, 1986

Publications

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