Yajuan J. Liu, PhD

Associate Professor

Yajuan J. Liu, PhD

E-mail:

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Office Location:

HSB - Room - H474-B

Mailing Address:

Box 357470
1959 NE Pacific St.
Seattle, WA 98195


Clinical and Research Background

Dr. Yajuan Liu joined the faculty in 2009, after her Clinical Cytogenetics Fellowship training at University of Washington. As one of the co-directors of our Clinical Cytogenetics and Genomics Laboratory, Dr. Liu is mainly responsible for bringing genomic testing using whole genome microarray analysis to our clinical lab. We have been offering whole genome microarray testing clinically for constitutional genetic disorders for both postnatal and prenatal diagnosis since 2010. We started to offer oncology genomic microarray testing for solid tumors and hematological neoplasms since 2012. Dr. Liu’s research interest is to do translational medicine using genomic approaches to aid the understanding of the etiology of cancers. Projects in her lab currently include: (1) Developing DNA sequence-based characterization of breakpoints of chromosome translocations/inversions in cancer using next generation sequencing. (2) Identifying new markers for Hepatitis C-associated hepatocellular carcinoma. (3) Correlating genetic alterations detected using genomic microarray and next generation sequencing with histology and clinical outcome in melanocytic neoplasms. (4) Using of genomic microarray analysis to rule in/out oncocytoma of the kidney in needle core biopsies. The main goals are to identify cancer biomarkers and novel therapeutic targets and to develop molecular diagnostics using both conventional genetics methods and new genomic approaches to aid in precision diagnostics for personalized care. She is also involved in the training of clinical fellows and residents at University of Washington.

Board Certifications

Clinical Cytogenetics, American Board of Medical Genetics

Clinical Molecular Genetics, American Board of Medical Genetics

Academic and Medical Appointments

Associate Professor, Department of Pathology, University of Washington, Seattle, WA, 2016-Present

Assistant Professor, Department of Pathology, University of Washington, Seattle, WA, 2009-2016

Co-Director of Clinical Cytogenetics and Genomics Laboratory, University of Washington Medical Center, Seattle, WA, 2009-Present

Senior Research Scientist, Departments of Biology and Genome Sciences, University of Washington, Seattle, WA, 2002-2007

Education and Training

Clinical Molecular Genetics Fellow, Department of Medicine, University of Washington, Seattle, WA, 2012-2013

Postdoctoral Fellow, Cancer Genetics, Department of Medicine, University of Washington, Seattle, WA, 2007-2009

Clinical Cytogenetics Fellow, Department of Medicine, University of Washington, Seattle, WA, 2007-2009

Postdoctoral Fellow, Yeast Genetics and Molecular Evolution. Departments of Biology and Genome Sciences, University of Washington, Seattle, WA, 1995-2002

State University of New York, College of Environmental Science & Forestry, Syracuse, NY, Molecular Biology, Ph.D., 1995

Wuhan University, Hubei, China, Genetics, Master of Science, 1989

Wuhan University, Hubei, China, Cell Biology, Bachelor of Science, 1986

Publications

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