Thomas J. Montine, MD, PhD

Professor and Chair

E-MAIL:
tmontine at uw.edu
MAIL/BOX #:
357470
OFFICE LOCATION:
HSB - Room C-516

 

Clinical/Research Background

Dr. Montine received his education at Columbia University (BA in Chemistry), the University of Rochester (PhD in Pharmacology), and McGill University (MD and CM). His postgraduate medical training was at Duke University, and he was junior faculty at Vanderbilt University where he was awarded the Thorne Professorship in Pathology.

Currently, Dr. Montine is the Alvord Endowed Chair in Neuropathology and Chair of the Department of Pathology at the University of Washington where he is Professor of Pathology and Adjunct Professor of Neurological Surgery; he also is Adjunct Professor of Neurology at Oregon Health & Science University. The Department of Pathology at the University of Washington, along with its affiliated institutions in Seattle, has over two hundred faculty, is consistently among the top Departments of Pathology in NIH funding, is a regional reference laboratory for pathology services in the Pacific Northwest, and is the Pathology training program for the Washington, Wyoming, Alaska, Montana, and Idaho (WWAMI) partnership.

Dr. Montine is the Director of the Pacific Northwest Udall Center (one of 10 NINDS-funded Morris K. Udall Centers of Excellence for Parkinson’s Disease Research) and is the Director of the University of Washington Alzheimer’s Disease Research Center (one of 15 such NIA-funded centers). Both of these national centers perform focused basic and translational research as well as clinical trials. Dr. Montine is the Director of the Alvord Brain Tumor Center that was initiated with an approximately $10 million philanthropic gift, and until 2010 was the Director of the Division of Neuropathology, which under his leadership attracted over $35 million in research funding from government and private foundations, and more than doubled its clinical service duties as it trained over two hundred and fifty students, residents, fellows, and visiting faculty. Dr. Montine is ranked among the top recipients of NIH funding among all Department of Pathology faculty in the United States and has been awarded the coveted “Teacher of the Quarter” award from the second year students in the School of Medicine.

The focus of the Montine Laboratory is on the structural and molecular bases of cognitive impairment in Alzheimer’s disease and Parkinson’s disease. Our goal is to define key pathogenic steps and thereby identify new potential therapeutic targets. The Montine Laboratory addresses these prevalent, unmet medical needs through a combination of epidemiologic neuropathology, biomarker development and application in clinical trials, and experimental studies that test hypotheses concerning specific mechanisms of neuron injury and approaches to neuroprotection in brain.  Google Scholar calculates Dr. Montine's H-Index as 71 and his I-10 Index as 232.

Board Certifications

Board Certified in Anatomic Pathology and Neuropathology

Academic/Medical Appointments

Current Appointments

Chair, Department of Pathology, University of Washington, Seattle, WA, 2010-Present

Alvord Endowed Chair in Neuropathology, University of Washington, Seattle, WA, 2002-Present

Director, Alzheimer's Disease Research Center, University of Washington, Seattle, WA, 2012-Present

Director, Pacific Northwest Udall Center, University of Washington and Oregon Health & Science University, 2009-Present

Adjunct Professor in Neurology, Oregon Health & Science University, Portland, OR, 2003-Present

Professor of Pathology and Adjunct Professor of Neurological Surgery, University of Washington, Seattle, WA, 2002-Present

Previous Appointments

Acting Chief of Service, Pathology, Harborview Medical Center, University of Washington, Seattle, WA, 2010-2011

Director, Division of Neuropathology, University of Washington, Seattle, WA, 2002-2010

Margaret and George Thorne Professorship in Pathology, Vanderbilt University, Nashville, TN, 2000-2002

Associate Professor of Pathology and Pharmacology, Vanderbilt University, Nashville, TN, 1999-2002

Assistant Professor of Pathology and Pharmacology, Vanderbilt University, Nashville, TN, 1996-1999

Clinical Responsibilities

Surgical Neuropathology, Seattle Cancer Care Alliance, Seattle, WA, 2006-Present

Surgical and Autopsy Neuropathology, UW Medicine, Seattle, WA, 2002-Present

Surgical and Autopsy Neuropathology, Vanderbilt University Medical Center, Nashville, TN, 1996-2002

Education and Training

Neuropathology Fellowship, Duke University, Durham, NC, 1993-1995

Pathology Residency, Duke University, Durham, NC, 1991-1993

MD, Master of Surgery (CM), McGill University, Montreal, Canada, 1991

PhD in Pharmacology, University of Rochester, Rochester, NY, 1988

BA in Chemistry, Columbia University, New York, NY, 1983

Publication and Grant Information

PubMed

Web of Science

Montine Lab