A. Sampath Narayanan, PhD

Professor Emeritus

A. Sampath Narayanan, PhD

E-mail:

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Office Location:

HSB - Room C-525

Mailing Address:

Box 357470
1959 NE Pacific St.
Seattle, WA 98195


Clinical and Research Background

Regulation of Fibroblast growth and Matrix synthesis during inflammation

For many years, we have been studying the extracellular matrix (ECM) particularly in two acquired diseases: chronic inflammation and fibrosis.

Fibroblasts are the major cell type responsible for ECM production in most connective tissues, and our laboratory has been studying the regulation of fibroblast growth and its ECM production by various cytokines and growth factors. Using the human idiopathic pulmonary fibrosis and chronic periodontitis as models for fibrosis and chronic inflammation, respectively, we are studying the importance of fibroblast subpopulations and local environment of the ECM in diseases and wound healing. We are attempting to define specific interactions between ECM components and fibroblasts and elucidate the biochemical signaling reactions that determine these interactions.

Academic and Medical Appointments

Professor Emeritus, Department of Pathology, University of Washington School of Medicine, Seattle, WA, 2013-Present

Professor, Department of Pathology, University of Washington School of Medicine, Seattle, WA, 2004-2013

Adjunct Professor, Oral Biology, University of Washington School of Medicine, Seattle, WA, Present

Research Professor, Department of Pathology, University of Washington School of Medicine, Seattle, WA , 1986-2004

Research Associate Professor, Department of Pathology, University of Washington School of Medicine, Seattle, WA , 1978-1986

Education and Training

National Institute of Dental Research Visiting Fellowship, 1969-1971

Postdoctoral Fellowship, Department of Pathology, University of Toronto, Toronto, ON, 1969

Medical Research Council Postdoctoral Fellowship, Department of Biochemistry, University of Toronto, Toronto, ON, 1967-1969

Council of Scientific and Industrial Research Fellowship, University of Madras Biochemistry Laboratory, Madras, India, 1963-1965

Doctorate of Philosophy, University of Madras, India, 1967

Master of Science, University of Madras, India, 1963

Bachelor of Science, University of Madras, India, 1961

Publications

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