Inversion

46,XY,inv(16)
This image shows an inversion of chromosome 16. By looking carefully att the pair of 16, you will see that the chromosome on the right looks different from the one on the left. The left one is normal and the right one is inverted near the centromere.

Inversions, by definition, do not involve loss or gain of chromosomal material. If the breakpoints of the inversion do not disrupt genes they may not have an associated phenotype.