Philadelphia Chromosome

The classic rearrangement seen in about 90% of patients with Chronic myelogenous leukemia (CML). It was originally thought to be a shortened 22 chromosome and dubbed the Philadelphia chromosome after the city in which it was discovered. Later determined to be a translocation between chromosomes 9 and 22 (part of 22 is attached to 9).

Back to Aquired Cytogenetic Abnormalities

To the UWMC Cytogenetics laboratory

Copyright 2003 Department of Pathology
Please refer to the Legality reference guide for terms of use.