Included in this issue:

January Meeting and Event Calendar

UWMC AP Conferences: Click here to access the UWMC Resident Didactic Conference Schedule.

Pathology Seminars: A list of seminars can be found on our Department of Pathology website.

UWMC Lecture Series Calendar
Launched in 1974, the Science in Medicine lecture series spans the Fall, Winter, and Spring Quarters and consists of thirteen lectures which recognize the outstanding research of our faculty. Visit their website for the schedule and more information.

Announcements

Fall 2005 Employee of the Quarter
The winner of the Fall 2005 Employee of the Quarter will be announced during second week of January. The Employee Recognition Team is currently reviewing the ten nominations that were submitted.

Save the Date: 2006 Pathology Holiday Party
Wednesday, December 13, 2006.

Save the Date: 2006 UWMC Holiday Party
Thursday, December 14, 2006.

Save the Date: 2006 Pathology Retreat
September 15-16, 2006 at the Sleeping Lady in Leavenworth, Washington. All faculty, residents, post-docs, grad students, and selected staff members are invited to attend.
LEAP Summit 2006
Interested in learing more about life science outreach programs in the Puget Sound Region? Attend LEAP Summit 2006 on Saturday, February 4th. LEAP: Life Sciences Education Advancement Partnership promotes discussion, articulation and collaboration amongst life sciences education outreach organizations, to better serve the Northwest community. To attend, please register at the LEAP Summit 2006 website.

The summit is a forum for teachers and school district administrators to discuss life sciences education outreach opportunities in the Puget Sound region. The goal of LEAP Summit 2006 is to increase awareness of regional science outreach programs, foster collaborations between existing programs, educators and industry for mutual benefit; and generate a resource guide for teachers, administrators and guidance counselors. If you'd like to know more about LEAP, please contact Steve Berard at sberard@u.washington.edu or 598-7475.

In the News

University of Washington Research Facts
The University of Washington is one of the nation's leading research universities. For the last 30 years, UW has ranked among the top five educational institutions in the nation for federal research funding. In recent years the UW has ranked first among public universities in the receipt of federal research grants and contracts.

Click here to view the UW Research Fact Sheet: A quick summary of UW research including funding statistics, nobel prize recipients, faculty honors, research centers, and the economic impact of research.

Path People

Holiday Party Recap
A special thanks to all who donated to the Noel House at the holiday party. Over one thousand dollars worth of food, clothing, personal health care products, and money have been donated to the Noel House the past three years. The Noel House is a local non-profit organization that provides safe and comfortable shelter for homeless women. Please visit the Noel House website for more information on their mission and for other ways to help throughout the year.

To view the photo gallery of the holiday party, click here. Most of the pictures were taken by six-year-old Jaedyn Colly, pictured on the right. Jaedyn is the grandson of Department of Pathology budget manager emeritus, Janet White. Jaedyn is a first grader at Emerson Elementary School in Seattle.
New PCS Support



Please welcome Sam Skjonsberg (l) and Brad Fulkerson (r) to the Pathology Computer Support team. Both are currently attending the University of Washington and will be assisting with all aspects of computer support. Their outstanding customer service skills and technical knowledge are a great addition to the department.
Grad Student News

Leslie Caromile, a 2nd year graduate student with the Department of Pathology in Professor Dan Bowen-Pope's lab, was recently named the AAAS (American Association for the Advancement of Science) "Next Wave" representative for UW graduate students. Leslie, pictured left, represents the grad school, communicating with the AAAS about relevant science symposia, speakers and general science doings on campus.

Leslie's thesis project involves Phogrin and IA-2 proteins that localize to insulin-containing secretory granules in pancreatic beta cells. This suggests that they play some role in regulating insulin secretion, but no enzymatic activity for Phogrin has ever been reported. In preliminary studies, Leslie has found that Phogrin is able to dephosphorylate specific inositol phospholipids. Domains that bind these phospholipids serve to localize specific proteins to the correct vesicle compartment and this regulates the formation and release of secretory vesicles. Leslie's thesis project is to confirm the enzymatic activity of Phogrin, determine the activity of IA-2, and test the hypothesis that Phogrin plays a role in regulating insulin release by maintaining a gradient of PIP levels between secretory vesicles and the plasma membrane. The proposed enzymatic activities of Phogrin and IA-2 provide steps at which the secretory pathway for insulin release may be mis-regulated in diabetes and/or manipulated for clinical benefit. She will also investigate the preliminary observation that modest elevation of circulating insulin levels, within the range found in type 2 diabetic patients, upregulates expression of Phogrin in vascular smooth muscle cells in injured vessels. This is the first observation of Phogrin expression outside of neuroendocrine cells. Leslie will test the hypothesis that elevated insulin levels specifically affect smooth muscle cells in injured vessels and that this might play a role in arterial disease in type 2 diabetic patients.

HR News

TAXES: "Nothing in life is certain except death and taxes." Benjamin Franklin

Your 2005 W-2 Tax Forms will be available for pickup on Wednesday, January 25, 2006 from 11:00 AM to 5:00 PM in the Pathology Payroll Office located in the Health Sciences Center, Room C-510. If you cannot pickup your tax form at that time, please email HR Pathology to request home delivery. Please verify that your current mailing address is correct on your MyUW Employee Self Service website. To update your address, go to the MyUw website, click on the ESS link and choose the Address Tab.

Inclement Weather/Suspended Operations Policy Reminder
The chill in the air should remind us all to be familiar with the University's inclement weather and suspended operations policies. Please note that the medical center is considered "essential services" and is excluded from the UW Suspended Operations policy. All administrative staff are required to report to work for their scheduled work day. Be sure to check the bus system snow day schedule to take an alternate bus if needed. If you will be late, be sure to call the front desk and your direct supervisor. If extenuating circumstances occur and it becomes impossible to come to work you must contact your direct supervisor. Last November new campus numbers took effect that provide information about operations at the three UW campuses during emergencies and severe weather conditions, updated to the minute.

Please take note of these numbers for up to date information on campus operations: 206-UWS-INFO (206-897-4636) and toll-free 1-866-897-4636

Also, please take a moment to familiarize yourself with following policies:

Inclement Weather

Suspended Operations

Transit News


Seattle Transit Tunnel
For construction updates on the Seattle Transit Tunnel and how it may impact your commute, please visit the
Seattle Transit Tunnel website.

Sound Transit Light Rail
And for information on the Sound Transit Light Rail project, including a future UW station, go to the
Sound Transit website.

If you have any comments or questions about the newsletter or would like to submit an item in the next issue, please contact Steve Berard at sberard@u.washington.edu or (206) 598-7475.