Flow Cytometry: Paraffin Specimens

General Recommendations for the Handling of Paraffin Specimens

Specimen Required

Paraffin block most representative of tumor to be analyzed and with highest ratio of tumor cells to normal. (Including a recent H&E reduces process time).

Return of Material

Blocks and/or slides are returned.

Flow Cytometry: Categories of Relevance to Prognosis, Treatment or Diagnosis

Proven value:

  • Barrett's Esophagus
  • Bladder
  • Breast Carcinoma
  • Endometrial Carcinoma
  • Molar pregnancy (products of conception)
  • Non-Hodgkin's Lymphoma
  • Ovarian Carcinoma
  • Prostate
  • Ulcerative Colitis

Probable value:

  • Adrenal Cortical Neoplasms
  • Chondrosarcoma/Osteogenic Sarcoma
  • Colon Carcinoma
  • Glioma ?
  • Melanoma ?
  • Multiple Myeloma
  • Renal Cell Carcinoma
  • Soft tissue Sarcoma
  • Squamous Carcinomas of Lung
  • Squamous Cell Carcinoma of Cervix ?

Uncertain value:

  • Carcinoid Tumors
  • Meningioma
  • Mesothelioma
  • Thyroid Neoplasms

Pathology Service Request Form Required

DNA Flow Cytometry Service Request Form

Include description of tissue source and copy of histologic diagnosis.

Flow Cytometry DNA Analysis Report

Report contains results including histogram, interpretation and supporting literature references.

Process Time

6 days from receipt