Maternal Cell Contamination Comparator
General Information
Lab Name
Maternal Cell Contamination Comparator
Lab Code
MCCOMP
Epic Name
Maternal Cell Contamination Comparator
Description
This test is for the comparator sample used to evaluate fetal tissue for contamination by maternal cells. It usually consists of a tube of whole blood from the mother; saliva and extracted DNA are also accepted.
Both this test and Maternal Cell Contamination, Fetal [MCC] must be ordered in order for the laboratory to perform maternal cell contamination studies.
See Maternal Cell Contamination, Fetal [MCC] for more information.
Synonyms
amniocyte contamination, control, DNA fingerprinting, fetal testing, Maternal Cell Contamination, MCC studies, prenatal testing
Interpretation
Reference Range
Ordering & Collection
Specimen Type
Collection
Whole blood:
5 mL LAVENDER TOP tube.
Also acceptable: YELLOW TOP (ACD) tube.
Unacceptable: Heparin green top tubes.
Extracted DNA:
1 ug (concentration >10 ng/uL).
Saliva:
Contact laboratory for validated collection kit.
Forms & Requisitions
Due to the complexity of prenatal testing, consultation with the laboratory is required.
Please contact the Genetics lab by e-mail (genelab@uw.edu) or phone (206-598-1149).
Outside providers: Genetics Requisition.
UW, HMC, and FHCC providers: Place order in Epic.
Handling Instructions
Whole blood: Refrigerate up to 1 week.
Extracted DNA: Frozen is preferred. Refrigerated is acceptable.
Saliva: Contact laboratory for a validated collection kit. Keep at room temperature.
Outside Laboratories
Whole blood: Ship at ambient temperature for receipt within 1 week of specimen collection.
Extracted DNA: Ship on a cold pack.
Saliva: Contact laboratory for a validated collection kit. Ship at room temperature.
Quantity
requested: Entire specimen.
minimum: Blood: 1 mL. Extracted DNA: 500 ng. Saliva: Per kit instructions.
Processing
Performance
LIS Dept Code
Genetics (GEN)
Performing Location(s)
| UW-MT |
Genetics
Attention: Genetics Lab Tel: 206-598–6429 M–F (7:30 AM–4:00 PM) Tel (EXOME only): 206-543-0459 |
Manager Variant Review Scientist Faculty |
|---|
Frequency
MCC studies are performed weekly once both the primary sample and comparator are received. Results within 2 weeks.
Available STAT?
No