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GRADUATE PROGRAM IN MOLECULAR BASIS OF DISEASECoursesCONJ 532 Signal Transduction from the Cell Membrane to the NucleusCourse Director: Beavo, Moon, StormQuarters Offered: Autumn Credits: 1.5 Intracellular signaling pathways leading from cell membrane receptors to nucleus. Pathways activated by seven transmembrane receptors and G-proteins, insulin/PI3 kinase, nitric oxide and WNTs and mechanisms of signal termination. Cytokine/Jak/Stat signaling and role of subcellular localization in signal transduction. Prerequisite: basic knowledge of biochemistry. |
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